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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAPLN4
All Species:
25.76
Human Site:
Y252
Identified Species:
62.96
UniProt:
Q86UW8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UW8
NP_075378.1
402
42801
Y252
A
N
G
G
L
R
N
Y
G
Y
R
H
N
A
E
Chimpanzee
Pan troglodytes
XP_524163
438
46405
Y288
A
N
G
G
L
R
N
Y
G
Y
R
H
N
A
E
Rhesus Macaque
Macaca mulatta
XP_001115151
402
42936
Y252
A
N
G
G
V
R
N
Y
G
Y
R
H
N
A
E
Dog
Lupus familis
XP_849484
354
40212
Y238
T
V
P
G
V
R
N
Y
G
F
W
D
K
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80WM4
400
42790
Y250
T
N
G
G
V
R
N
Y
G
Y
R
H
N
A
E
Rat
Rattus norvegicus
P03994
354
40243
Y238
T
V
P
G
V
R
N
Y
G
F
W
D
K
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509283
354
40324
Y238
T
V
P
G
V
R
N
Y
G
F
W
D
K
D
K
Chicken
Gallus gallus
P07354
355
40514
Y239
T
V
P
G
V
R
N
Y
G
F
W
D
K
E
R
Frog
Xenopus laevis
NP_001079631
359
40867
Y245
T
A
P
G
V
R
S
Y
G
E
R
H
K
Q
L
Zebra Danio
Brachydanio rerio
NP_001038372
344
39138
Y216
R
H
K
D
D
E
R
Y
D
A
F
C
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
98.7
44
N.A.
91
43.7
N.A.
43.7
43.7
42
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.7
99
57.4
N.A.
92.7
57.4
N.A.
57.9
57.2
56.2
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
33.3
N.A.
86.6
33.3
N.A.
33.3
33.3
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
93.3
53.3
N.A.
53.3
46.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
0
0
0
0
0
0
0
10
0
0
0
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
10
0
0
40
0
30
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
40
10
0
10
0
0
% F
% Gly:
0
0
40
90
0
0
0
0
90
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
50
0
30
% K
% Leu:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
80
0
0
0
0
0
40
0
0
% N
% Pro:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
0
0
0
90
10
0
0
0
50
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% S
% Thr:
60
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
40
0
0
70
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
40
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _